ISAR-REACT score
Also written as: ISAR-REACT — Intracoronary Stenting and Antithrombotic Regimen-Rapid Early Action for Coronary Treatment
Risk stratification tool for predicting thrombotic complications in patients undergoing PCI with different antiplatelet strategies.
Full Definition
The ISAR-REACT score is a clinical risk assessment tool derived from the Intracoronary Stenting and Antithrombotic Regimen-Rapid Early Action for Coronary Treatment trials. This scoring system stratifies patients into low, intermediate, and high-risk categories for thrombotic events during percutaneous coronary intervention based on clinical and angiographic variables. The score incorporates factors such as age, diabetes mellitus, acute coronary syndrome presentation, multivessel disease, and lesion characteristics. ISAR-REACT helps guide antiplatelet therapy decisions, particularly regarding the use of glycoprotein IIb/IIIa inhibitors in addition to dual antiplatelet therapy. Higher scores indicate increased thrombotic risk and potential benefit from more intensive antiplatelet regimens.
Usage
Usage note: Always capitalize and hyphenate ISAR-REACT; include 'score' when referencing the risk tool.
In Context
- "The patient's ISAR-REACT score was 3, placing him in the high-risk category for thrombotic complications." — Pre-procedure risk assessment
- "Given the low ISAR-REACT score, glycoprotein IIb/IIIa inhibitor use was deferred." — Interventional cardiology note