TVR
Also written as: TVR — Target Vessel Revascularization
Target vessel revascularization encompassing any repeat intervention in the entire target coronary vessel, broader than target lesion revascularization.
Full Definition
Target vessel revascularization (TVR) is defined as repeat percutaneous or surgical revascularization of any segment of the target vessel, extending beyond the immediate target lesion to include the entire coronary vessel from ostium to apex. TVR encompasses both target lesion revascularization and revascularization of other segments within the same vessel due to disease progression or procedural complications. This endpoint provides a vessel-level assessment of treatment effectiveness and captures both local device effects and vessel-wide disease progression. TVR classification requires careful anatomical definition of vessel boundaries, particularly at bifurcation points and in the setting of chronic total occlusions where collateral circulation may complicate vessel territory definition.
Usage
Usage note: Broader than TLR; specify vessel territory boundaries clearly, especially in multivessel disease scenarios.
In Context
- "TVR rates at 2 years included both target lesion and remote target vessel interventions (8.4% vs 14.7%, p=0.02)." — Extended follow-up analysis
- "The study protocol distinguished clinically driven TVR from angiographically driven TVR based on symptom status." — Endpoint adjudication guidelines