Skip to main content
Intermediate Technical IVT

SSRI

Also written as: SSRI — Selective Serotonin Reuptake Inhibitor

Class of antidepressant medications commonly prescribed for anxiety and mood disorders in children and adolescents.

Full Definition

Selective Serotonin Reuptake Inhibitors are a class of psychiatric medications that increase serotonin levels in the brain by blocking its reabsorption. In child and adolescent psychiatry, SSRIs are first-line treatments for major depressive disorder, anxiety disorders, and obsessive-compulsive disorder. Common SSRIs include fluoxetine, sertraline, and escitalopram. These medications require careful monitoring for side effects, particularly increased suicidal ideation in youth under 25. The FDA has issued black box warnings for all antidepressants regarding suicide risk in pediatric populations.

Usage

Usage note: Always use caps for the acronym; include black box warning information when discussing with families.

In Context

  • "The patient showed significant improvement on the SSRI after six weeks of treatment." — Clinical progress note
  • "SSRI medications require close monitoring for suicidal ideation in adolescent patients." — Treatment protocol

Also known as

Selective Serotonin Reuptake Inhibitor

Contrasted with

SNRI tricyclic antidepressant

Don't confuse with

SNRI MAOI

Editors from these organisations have used our services since 1998

Reuters BBC Oxford University Press Penguin Random House Springer Microsoft Suncor Energy United Nations Fisher Investments IBM The Home Depot KODAK CHEVRON