Epileptic Encephalopathy
A condition where epileptic activity contributes to progressive cognitive and behavioral deterioration beyond what would be expected from underlying pathology alone.
Full Definition
Epileptic encephalopathy is a concept describing epilepsies where seizures and interictal epileptiform activity contribute to progressive disturbance of cerebral function, resulting in cognitive, behavioral, and sometimes motor regression. The term emphasizes that the epileptic activity itself, not just the underlying etiology, contributes to developmental impairment. Examples include West syndrome, Dravet syndrome, and Ohtahara syndrome. Early recognition and aggressive treatment are crucial to minimize long-term developmental consequences.
Usage
Usage note: Distinguish from 'developmental and epileptic encephalopathy' which has a broader definition.
In Context
- "The child's regression suggested an epileptic encephalopathy requiring immediate intervention." — Urgent consultation note
- "Early treatment of epileptic encephalopathy may prevent further developmental decline." — Treatment guideline