PLEDs
Pronunciation: PLEDS
Also written as: PLEDs — Periodic Lateralized Epileptiform Discharges
Periodic lateralized epileptiform discharges; repetitive sharp waves or spikes occurring at regular intervals, typically indicating acute brain injury.
Full Definition
Periodic lateralized epileptiform discharges (PLEDs) are repetitive sharp waves, spikes, or sharp-and-slow wave complexes that occur at regular intervals, typically every 0.5-3 seconds, and are lateralized to one hemisphere. PLEDs are considered an ictal-interictal continuum pattern and often indicate acute destructive brain lesions such as stroke, encephalitis, or tumor. They may be associated with clinical seizures or represent a form of non-convulsive status epilepticus. The pattern is important for prognosis and treatment decisions in critically ill patients.
Usage
Usage note: Note: this is different from the existing term 'periodic lateralized epileptiform discharges' listed by user - PLEDs is the standard abbreviation.
In Context
- "The EEG showed PLEDs over the left hemisphere following the patient's embolic stroke." — Acute stroke evaluation
- "PLEDs were noted in the right temporal region and were associated with subtle focal seizures." — ICU monitoring report