Cutaneous Lymphoma
A heterogeneous group of lymphoid malignancies primarily affecting the skin. Includes both T-cell and B-cell variants requiring specialized staging and treatment.
Full Definition
Cutaneous lymphomas represent a diverse group of extranodal lymphoid neoplasms that primarily manifest in the skin. The most common form is mycosis fungoides, a T-cell lymphoma that progresses through patch, plaque, and tumor stages. Primary cutaneous B-cell lymphomas are less common but include marginal zone and large B-cell subtypes. These malignancies require specialized staging systems distinct from nodal lymphomas and often present diagnostic challenges due to their inflammatory appearance. Treatment approaches range from topical therapies for early-stage disease to systemic chemotherapy for advanced cases, with dermatologic surgeons playing crucial roles in diagnosis and local management.
Usage
Usage note: Always specify T-cell or B-cell subtype when known.
In Context
- "The biopsy confirmed cutaneous lymphoma with predominant T-cell population and epidermotropism." — pathology report
- "Staging workup for cutaneous lymphoma revealed no evidence of systemic involvement." — oncology consultation