Intermediate
Technical
In the Industry Vocabulary Test
dual antiplatelet therapy
Combination treatment with aspirin plus a P2Y12 inhibitor to prevent thrombotic events.
Full Definition
A pharmacological strategy combining aspirin with a P2Y12 receptor antagonist (such as clopidogrel, prasugrel, or ticagrelor) to provide enhanced platelet inhibition in patients with acute coronary syndromes or following percutaneous coronary intervention. The duration and choice of agents depend on patient risk factors, bleeding risk, and clinical presentation. This therapy significantly reduces the risk of stent thrombosis and recurrent ischemic events.
Usage
Usage note: Spell out on first use, may abbreviate as DAPT subsequently.
In Context
- "The patient was discharged on dual antiplatelet therapy with aspirin and ticagrelor for 12 months." — Discharge summary
- "Dual antiplatelet therapy was held prior to urgent surgery due to bleeding risk." — Perioperative note
Also known as
DAPT
Contrasted with
single antiplatelet therapy
Don't confuse with
anticoagulation
triple therapy