takotsubo cardiomyopathy
Pronunciation: tah-ko-TSOO-bo
Stress-induced reversible heart muscle dysfunction mimicking acute coronary syndrome.
Full Definition
Takotsubo cardiomyopathy, also known as stress cardiomyopathy or broken heart syndrome, is a transient left ventricular dysfunction that mimics acute coronary syndrome but occurs without significant coronary artery disease. The condition is characterized by distinctive wall motion abnormalities, typically apical ballooning that gives the left ventricle an appearance similar to a Japanese octopus trap (takotsubo). It commonly affects postmenopausal women following emotional or physical stress. Patients present with chest pain, ECG changes, and elevated cardiac enzymes, but coronary angiography reveals normal or near-normal coronary arteries. The condition is generally reversible with supportive care, though complications can include heart failure, arrhythmias, and rarely, left ventricular rupture.
Usage
Usage note: Japanese origin; no need for italics in medical writing; hyphenate compound forms.
In Context
- "Coronary angiography was normal, confirming the diagnosis of takotsubo cardiomyopathy." — Cardiology consultation note
- "The patient developed takotsubo cardiomyopathy following her husband's sudden death." — Hospital discharge summary