Lymph Node Central Compartment
The anatomical region containing lymph nodes at highest risk for metastasis from thyroid cancer.
Full Definition
The central compartment (Level VI) is the primary lymphatic drainage region for the thyroid gland, bounded by the carotid arteries laterally, the hyoid bone superiorly, and the innominate vessels inferiorly. This compartment contains the pretracheal, paratracheal, and prelaryngeal (Delphian) lymph nodes, which are the most common sites of thyroid cancer metastasis. Central compartment lymph node dissection may be performed prophylactically or therapeutically during thyroid cancer surgery. Involvement of central compartment nodes affects staging and may influence decisions regarding radioactive iodine therapy and long-term surveillance protocols.
Usage
Usage note: May be referred to as Level VI; distinguish from lateral neck compartments.
In Context
- "Intraoperative examination revealed enlarged lymph nodes in the central compartment." — Operative report
- "Central compartment dissection yielded three positive lymph nodes out of eight examined." — Pathology report