Professional
Technical
IVT
PRRT
Also written as: PRRT — Peptide Receptor Radionuclide Therapy
A targeted radiotherapy treatment for somatostatin receptor-positive neuroendocrine tumors.
Full Definition
Peptide Receptor Radionuclide Therapy (PRRT) is a molecularly targeted treatment that delivers radiation directly to neuroendocrine tumor cells expressing somatostatin receptors. The therapy uses radiolabeled somatostatin analogs, most commonly lutetium-177 DOTATATE, which bind to receptors on tumor cells and deliver localized radiation. PRRT is indicated for well-differentiated, somatostatin receptor-positive neuroendocrine tumors and has shown significant benefit in progression-free survival.
Usage
Usage note: Always spell out on first use in documents.
In Context
- "The patient completed four cycles of PRRT with lutetium-177 DOTATATE." — treatment summary
- "PRRT eligibility requires positive somatostatin receptor imaging and adequate kidney function." — treatment protocol
Also known as
peptide receptor radionuclide therapy
targeted radiotherapy
Don't confuse with
PSMA therapy
radioimmunotherapy