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Professional Technical In the Industry Vocabulary Test

Responsive neurostimulation

Also written as: RNS

An implantable device that detects abnormal brain activity and delivers targeted electrical stimulation to prevent seizures.

Full Definition

Responsive neurostimulation (RNS) is a closed-loop brain stimulation system designed for patients with medically refractory epilepsy who are not candidates for resective surgery. The system continuously monitors brain activity through implanted electrodes and automatically delivers brief electrical pulses when abnormal patterns are detected. Unlike continuous stimulation devices, RNS only activates when seizure-like activity is identified, potentially reducing side effects and battery consumption. The FDA-approved RNS System has shown efficacy in reducing seizure frequency in focal epilepsy patients.

Usage

Usage note: Often abbreviated as RNS in clinical documentation.

In Context

  • "The patient was evaluated for responsive neurostimulation after failing multiple resective surgery evaluations." — Surgical consultation
  • "Responsive neurostimulation data showed a 60% reduction in disabling seizures at 12 months." — Follow-up report

Also known as

RNS closed-loop neurostimulation

Contrasted with

open-loop stimulation

Don't confuse with

deep brain stimulation vagal nerve stimulation

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