chorioamnionitis
Pronunciation: kor-ee-oh-am-nee-oh-NY-tis
Bacterial infection of the fetal membranes and amniotic fluid during pregnancy, potentially causing maternal and fetal complications.
Full Definition
Chorioamnionitis is an inflammatory condition caused by bacterial infection of the chorion, amnion, and amniotic fluid. This condition affects 1-5% of pregnancies and is more common with prolonged rupture of membranes, prolonged labor, and multiple vaginal examinations. Clinical signs include maternal fever, uterine tenderness, foul-smelling amniotic fluid, maternal and fetal tachycardia, and elevated white blood cell count. Chorioamnionitis can lead to serious complications including preterm birth, neonatal sepsis, cerebral palsy, and maternal sepsis. Treatment typically involves antibiotic therapy and expedited delivery.
Usage
Usage note: Distinguish between clinical and histologic chorioamnionitis in documentation.
In Context
- "Clinical chorioamnionitis was diagnosed based on maternal fever and uterine tenderness." — Labor and delivery admission note