PPROM
Pronunciation: PEE-prom
Also written as: PPROM — Preterm Premature Rupture of Membranes
Preterm premature rupture of membranes occurring before 37 weeks of gestation.
Full Definition
PPROM (preterm premature rupture of membranes) is defined as rupture of the chorioamniotic membranes before the onset of labor and before 37 completed weeks of gestation. This condition complicates approximately 2-3% of pregnancies and is responsible for about one-third of preterm deliveries. PPROM can lead to serious complications including preterm birth, neonatal sepsis, respiratory distress syndrome, intraventricular hemorrhage, and necrotizing enterocolitis. Risk factors include previous PPROM, intrauterine infection, cervical incompetence, and polyhydramnios. Management involves balancing the risks of prematurity against the risks of infection, often requiring hospitalization, antibiotic prophylaxis, corticosteroids for fetal lung maturity, and careful monitoring for signs of infection or labor.
Usage
Usage note: Distinguish from PROM, which occurs at term; the 'preterm' designation is crucial.
In Context
- "PPROM was diagnosed at 28 weeks, and the patient was admitted for expectant management." — Hospital admission note
- "Betamethasone was administered for fetal lung maturity following PPROM at 32 weeks gestation." — Treatment plan