CCAM
Also written as: CCAM — Congenital Cystic Adenomatoid Malformation
Congenital cystic adenomatoid malformation, a developmental lung lesion with cystic and solid components.
Full Definition
Congenital cystic adenomatoid malformation (CCAM) is a rare developmental anomaly of the lung characterized by multicystic masses that replace normal lung tissue. These lesions are classified into five types based on cyst size and histological features. Large CCAMs can cause mediastinal shift, polyhydramnios, and hydrops fetalis due to compression of normal structures. Fetal surgical intervention may be indicated for lesions with a high CCAM volume ratio that predict poor outcomes.
Usage
Usage note: CPAM (congenital pulmonary airway malformation) is the newer preferred terminology, but CCAM remains widely used in clinical practice.
In Context
- "The Type I CCAM measured 4.2 cm and showed a CCAM volume ratio of 1.8, indicating high risk for hydrops." — Ultrasound report
- "Fetal lobectomy was performed for the large CCAM causing significant mediastinal shift." — Surgical report