Intermediate
Technical
IVT
Barrett's esophagus
Pronunciation: BARE-ets
Precancerous condition where normal esophageal squamous epithelium is replaced by intestinal-type columnar epithelium.
Full Definition
Barrett's esophagus is a premalignant condition characterized by the replacement of the normal stratified squamous epithelium of the distal esophagus with intestinal-type metaplastic columnar epithelium containing goblet cells. This metaplastic change typically results from chronic gastroesophageal reflux and represents a significant risk factor for the development of esophageal adenocarcinoma. Surveillance endoscopy with biopsy is recommended for cancer detection and risk stratification.
Usage
Usage note: Retain possessive apostrophe; capitalize Barrett as eponym; specify length when clinically relevant.
In Context
- "Surveillance endoscopy revealed high-grade dysplasia within Barrett's esophagus." — Endoscopy report
- "The patient's 5-cm segment of Barrett's esophagus required radiofrequency ablation." — Treatment planning document
Also known as
columnar-lined esophagus
intestinal metaplasia of esophagus
Don't confuse with
esophagitis
dysplasia
squamous cell carcinoma