pancreatic fistula
An abnormal connection between the pancreatic duct and other structures, causing pancreatic juice to leak outside the normal pathway.
Full Definition
A pancreatic fistula is a serious complication that can occur after pancreatic surgery, particularly following pancreaticoduodenectomy or distal pancreatectomy. It results from failure of the pancreatic anastomosis to heal properly, causing pancreatic enzymes to leak into the abdominal cavity or through external drainage sites. The International Study Group on Pancreatic Fistula (ISGPF) has established grading criteria (Grade A, B, or C) based on clinical impact. Grade A fistulas are biochemical leaks without clinical consequences, while Grade B and C fistulas require intervention and can lead to significant morbidity including infection, hemorrhage, and prolonged hospitalization.
Usage
Usage note: Grade using ISGPF criteria (A, B, C); distinguish from other types of fistulas.
In Context
- "The patient developed a Grade B pancreatic fistula on postoperative day 5, requiring percutaneous drainage." — Postoperative complication note
- "Drain amylase levels were monitored to detect early signs of pancreatic fistula formation." — Postoperative monitoring protocol