Intermediate
Technical
IVT
pCR
Pronunciation: p-c-r
Also written as: pCR — pathological complete response
Pathological complete response indicating absence of viable tumor cells after neoadjuvant treatment.
Full Definition
Pathological complete response (pCR) refers to the complete absence of viable tumor cells in the primary tumor site and regional lymph nodes following neoadjuvant chemotherapy or chemoradiotherapy. This finding on surgical pathology examination is considered a favorable prognostic indicator and surrogate endpoint for treatment efficacy. Editorial guidance: Distinguish from radiological complete response and ensure proper context when abbreviated.
Usage
Usage note: Always spell out on first use in documents; avoid confusion with PCR (polymerase chain reaction).
In Context
- "The patient achieved pCR following FLOT chemotherapy prior to gastrectomy." — Oncology treatment summary
- "pCR rates were significantly higher in the experimental arm of the clinical trial." — Clinical trial report
Also known as
pathological complete response
pathologic complete response
Contrasted with
residual disease
partial response
Don't confuse with
PCR (polymerase chain reaction)
clinical complete response