HFrEF
Also written as: HFrEF — Heart Failure with reduced Ejection Fraction
Heart failure characterized by left ventricular ejection fraction below 40%, distinguished from HFpEF in geriatric populations.
Full Definition
Heart failure with reduced ejection fraction represents a specific phenotype of heart failure where the left ventricle's pumping ability is significantly impaired, with ejection fraction below 40%. In geriatric cardiology, HFrEF often presents differently than in younger patients, with more comorbidities and polypharmacy considerations. Management requires careful titration of evidence-based medications while considering age-related physiological changes and potential drug interactions. The condition is associated with higher mortality rates in elderly patients.
Usage
Usage note: Always spell out on first use; distinguish clearly from HFpEF in clinical documentation.
In Context
- "The 78-year-old patient's echocardiogram confirmed HFrEF with an ejection fraction of 35%." — Cardiology consultation note
- "Guideline-directed medical therapy for HFrEF must be carefully adjusted in geriatric patients." — Clinical practice guideline