consolidation therapy
Additional treatment given after primary therapy to maintain response and prevent recurrence, commonly used in ovarian cancer management.
Full Definition
Consolidation therapy refers to additional treatment administered following primary therapy to consolidate the therapeutic response and reduce the risk of disease recurrence. In gynecologic oncology, this concept is most commonly applied in ovarian cancer management, where maintenance therapies such as PARP inhibitors or bevacizumab are given after completion of primary chemotherapy. The goal is to prolong the disease-free interval and potentially improve overall survival by targeting minimal residual disease. Consolidation therapy decisions are based on factors including initial response to treatment, molecular characteristics of the tumor, and patient tolerability. This approach represents an evolution from the traditional watch-and-wait strategy following primary treatment.
Usage
Usage note: Specify the agent and duration when describing consolidation therapy regimens.
In Context
- "The patient achieved complete response to primary chemotherapy and will begin consolidation therapy with a PARP inhibitor." — Treatment plan
- "Consolidation therapy with bevacizumab was continued for 15 months following completion of carboplatin and paclitaxel." — Treatment summary