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Professional Technical IVT

platinum-sensitive

Disease that recurs more than six months after completing platinum-based chemotherapy.

Full Definition

Platinum-sensitive recurrence refers to ovarian cancer that relapses more than six months after the completion of first-line or subsequent platinum-based chemotherapy regimens. This classification is clinically significant because platinum-sensitive tumors typically respond well to retreatment with platinum agents. The six-month threshold is a key prognostic indicator and influences treatment selection, with platinum-sensitive patients often receiving combination platinum therapy upon recurrence.

Usage

Usage note: The six-month cutoff is crucial for accurate classification.

In Context

  • "The patient's platinum-sensitive recurrence at 14 months made her eligible for carboplatin-based retreatment." — treatment plan
  • "Platinum-sensitive patients demonstrated superior response rates in the clinical trial." — research publication

Also known as

platinum-responsive

Contrasted with

platinum-resistant platinum-refractory

Don't confuse with

platinum-eligible platinum-naive

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