platinum-sensitive
Disease that recurs more than six months after completing platinum-based chemotherapy.
Full Definition
Platinum-sensitive recurrence refers to ovarian cancer that relapses more than six months after the completion of first-line or subsequent platinum-based chemotherapy regimens. This classification is clinically significant because platinum-sensitive tumors typically respond well to retreatment with platinum agents. The six-month threshold is a key prognostic indicator and influences treatment selection, with platinum-sensitive patients often receiving combination platinum therapy upon recurrence.
Usage
Usage note: The six-month cutoff is crucial for accurate classification.
In Context
- "The patient's platinum-sensitive recurrence at 14 months made her eligible for carboplatin-based retreatment." — treatment plan
- "Platinum-sensitive patients demonstrated superior response rates in the clinical trial." — research publication