McCrea-Marshall syndrome
A rare condition involving vaginal agenesis with functional uterine tissue, requiring specialized surgical management.
Full Definition
McCrea-Marshall syndrome, also known as Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, is a congenital condition characterized by the absence or underdevelopment of the vagina and uterus in individuals with normal ovarian function and external genitalia. The condition presents with primary amenorrhea in otherwise normally developing individuals. Management typically involves creating a functional vagina through surgical techniques such as McIndoe procedure or intestinal vaginoplasty, or non-surgical methods using progressive dilation. The psychological and sexual health implications require comprehensive, multidisciplinary care approaches.
Usage
Usage note: Multiple acceptable names; MRKH is commonly used abbreviation in literature.
In Context
- "The diagnosis of McCrea-Marshall syndrome was confirmed with MRI showing absent uterine and vaginal development." — pediatric gynecology consultation
- "Counseling for McCrea-Marshall syndrome should address both surgical options and fertility implications." — patient counseling documentation