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Professional Technical IVT

parametrial invasion

Extension of cervical cancer into the parametrial tissues, indicating locally advanced disease.

Full Definition

Parametrial invasion refers to the extension of cervical carcinoma beyond the cervix into the parametrial tissues, which include the cardinal and uterosacral ligaments. This finding indicates locally advanced cervical cancer and typically corresponds to FIGO stage IIB disease. Parametrial invasion significantly impacts prognosis and treatment planning, often necessitating chemoradiation therapy rather than primary surgical management. The diagnosis may be made clinically through pelvic examination, or radiologically through MRI imaging. Histopathologic confirmation requires examination of parametrial tissues obtained during radical hysterectomy.

Usage

Usage note: Critical for staging; distinguish from other forms of local extension.

In Context

  • "MRI imaging demonstrated parametrial invasion, upstaging the cervical cancer to IIB." — Radiology report
  • "Histopathologic examination confirmed parametrial invasion with tumor extending to the cardinal ligament." — Pathology report

Also known as

parametrial extension

Don't confuse with

vaginal invasion bladder invasion

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