LSIL
Pronunciation: EL-sil
Also written as: LSIL — Low-grade Squamous Intraepithelial Lesion
Low-grade squamous intraepithelial lesion; a Pap smear result indicating mild cervical cell abnormalities.
Full Definition
LSIL (Low-grade Squamous Intraepithelial Lesion) is a category in the Bethesda System for reporting cervical cytology results. It represents mild abnormalities in the squamous cells of the cervix, typically associated with HPV infection. LSIL corresponds to cervical intraepithelial neoplasia grade 1 (CIN 1) in histological terms and includes cellular changes such as koilocytosis and mild dysplasia. Most LSIL cases resolve spontaneously, particularly in younger women, as the immune system clears the HPV infection. Management typically involves repeat cytology or HPV testing, with colposcopy reserved for persistent cases or specific risk factors.
Usage
Usage note: Always use all capitals; part of standardized Bethesda System terminology for cervical cytology.
In Context
- "The cytology report showed LSIL, and the patient will return for repeat Pap testing in 12 months." — pathology report
- "Given the patient's age of 23 and LSIL result, we recommend conservative management with repeat cytology." — consultation note