Karnofsky Performance Scale
Also written as: KPS — Karnofsky Performance Scale
Functional status assessment tool using percentage scores (0-100%) to evaluate cancer patient activity levels. Alternative to ECOG performance status in oncology trials.
Full Definition
The Karnofsky Performance Scale (KPS) is a widely used assessment tool that measures cancer patients' functional status and overall well-being using percentage scores ranging from 0% (dead) to 100% (normal activity without symptoms). Developed by David Karnofsky in 1948, the scale evaluates patients' ability to perform daily activities, work capacity, and care requirements. In head and neck oncology, KPS scores influence treatment selection, clinical trial eligibility, and prognosis determination. Scores of 70% or higher generally indicate good functional status suitable for aggressive treatment approaches, while lower scores may necessitate palliative care considerations or modified treatment regimens.
Usage
Usage note: Uses percentages unlike ECOG (0-5 scale); distinguish between the two systems.
In Context
- "The patient's Karnofsky Performance Scale score of 80% supported candidacy for concurrent chemoradiation therapy." — Treatment planning note
- "Study inclusion required a minimum Karnofsky Performance Scale score of 70% at baseline assessment." — Clinical trial protocol