lymphadenopathy
Pronunciation: lim-fad-eh-NOP-ah-thee
Abnormal enlargement of lymph nodes, which may indicate infection, autoimmune disease, or malignancy including lymphomas.
Full Definition
Lymphadenopathy refers to the abnormal enlargement of lymph nodes, typically defined as nodes larger than 1 cm in diameter in most anatomical regions. In hematologic oncology, lymphadenopathy is a key clinical finding that may indicate lymphoma, leukemia with nodal involvement, or other hematologic malignancies. The pattern, size, consistency, and location of enlarged lymph nodes provide important diagnostic clues. Lymphadenopathy may be localized to one region or generalized throughout multiple lymph node groups, and its characteristics help guide further evaluation and staging procedures.
Usage
Usage note: Single word, not hyphenated; distinguish from lymphangiopathy (lymphatic vessel disease) and lymphedema (tissue swelling).
In Context
- "Physical examination revealed significant cervical and axillary lymphadenopathy." — Clinical examination note
- "CT imaging showed mediastinal lymphadenopathy consistent with lymphoma staging." — Radiology report