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Gonadotropin-Releasing Hormone
A hypothalamic hormone that stimulates pituitary release of LH and FSH.
Full Definition
Gonadotropin-releasing hormone (GnRH) is a decapeptide synthesized in the hypothalamus that controls reproductive hormone production. GnRH is released in pulsatile fashion and travels through the hypothalamic-hypophyseal portal system to stimulate gonadotroph cells in the anterior pituitary. This stimulation results in LH and FSH secretion, which then act on the gonads to regulate reproductive function. GnRH testing and stimulation tests are used to evaluate hypothalamic-pituitary-gonadal axis function.
Usage
Usage note: Include hyphens in full form; use 'GnRH' abbreviation after first mention.
In Context
- "GnRH stimulation testing helps differentiate hypothalamic from pituitary causes of hypogonadism." — Endocrinology diagnostic protocol
- "Continuous gonadotropin-releasing hormone administration suppresses reproductive function." — Treatment protocol documentation
Also known as
GnRH
LHRH
Luteinizing hormone-releasing hormone
Don't confuse with
LH
FSH
hCG