Advanced
Technical
IVT
Inhibin B
A gonadal hormone that inhibits FSH secretion, used as a marker of ovarian and testicular function.
Full Definition
Inhibin B is a glycoprotein hormone produced by granulosa cells in ovarian follicles and Sertoli cells in the testes that provides negative feedback to the pituitary gland by suppressing FSH secretion. In women, inhibin B levels reflect the number and quality of developing follicles, making it a valuable marker of ovarian reserve. In men, inhibin B correlates with Sertoli cell function and spermatogenesis. Inhibin B testing is used in fertility assessment, evaluation of ovarian reserve, and monitoring of testicular function.
Usage
Usage note: Distinguish from inhibin A, which is measured in pregnancy screening.
In Context
- "Low inhibin B levels indicated diminished ovarian reserve in the 38-year-old patient." — Fertility consultation
- "Inhibin B measurement complemented the ovarian reserve assessment along with AMH and antral follicle count." — Reproductive endocrinology report
Contrasted with
Activin
Don't confuse with
Inhibin A
Anti-Müllerian Hormone