anhydramnios
Pronunciation: an-hahy-DRAM-nee-ohs
Complete absence of amniotic fluid, representing the most severe form of oligohydramnios with significant fetal implications.
Full Definition
Anhydramnios refers to the complete absence of amniotic fluid around the developing fetus, representing the most severe end of the oligohydramnios spectrum. This rare condition is typically associated with severe fetal renal anomalies (such as bilateral renal agenesis or severe cystic kidney disease), prolonged rupture of membranes, or severe placental insufficiency. Anhydramnios results in characteristic fetal deformities including pulmonary hypoplasia, growth restriction, and Potter sequence (distinctive facial features and limb deformities). The condition carries a grave prognosis due to severe lung underdevelopment and associated anomalies. Prenatal diagnosis is made by ultrasound demonstration of absent amniotic fluid pockets.
Usage
Usage note: Most severe form of oligohydramnios; use precisely to indicate complete absence of fluid.
In Context
- "Ultrasound findings of anhydramnios and bilateral renal agenesis indicated a lethal fetal condition." — Maternal fetal medicine consultation
- "The diagnosis of anhydramnios prompted genetic counseling and discussion of pregnancy termination options." — Prenatal diagnosis report