cordocentesis
Pronunciation: kor-do-sen-TEE-sis
A prenatal diagnostic procedure involving needle sampling of fetal blood directly from the umbilical cord.
Full Definition
Cordocentesis, also known as percutaneous umbilical blood sampling (PUBS), is an invasive prenatal diagnostic procedure performed under ultrasound guidance. A needle is inserted through the maternal abdomen and uterine wall to access fetal blood directly from the umbilical cord, typically at the placental insertion site. This procedure allows for rapid karyotyping, blood gas analysis, and diagnosis of fetal infections or hematologic disorders. It is usually performed after 18 weeks of gestation and carries a slightly higher risk of complications compared to amniocentesis, including bleeding, infection, and fetal bradycardia.
Usage
Usage note: May be abbreviated as PUBS in clinical notes. The 'cord' refers to umbilical cord, not spinal cord.
In Context
- "Cordocentesis was performed to rapidly assess fetal karyotype in the setting of multiple anomalies." — Procedure note
- "The patient consented to cordocentesis after thorough discussion of risks and benefits." — Informed consent documentation