TORCH
Also written as: TORCH — Toxoplasmosis, Other, Rubella, Cytomegalovirus, Herpes
An acronym for a group of infections that can cause congenital anomalies when acquired during pregnancy.
Full Definition
TORCH is an acronym representing a group of infectious agents that can cause significant congenital anomalies when maternal infection occurs during pregnancy. The traditional acronym stands for Toxoplasmosis, Other (including syphilis, varicella, HIV), Rubella, Cytomegalovirus, and Herpes simplex virus. These infections can cross the placental barrier and affect fetal development, potentially causing growth restriction, developmental delays, organ malformations, and neurological deficits. TORCH screening may be performed when fetal anomalies are detected or when maternal infection is suspected. Modern expanded versions include additional pathogens such as Zika virus and parvovirus B19.
Usage
Usage note: Use all capitals. The 'O' in Other has evolved to include various pathogens beyond the original definition.
In Context
- "TORCH titers were drawn to evaluate for possible congenital infection given the fetal growth restriction." — Laboratory order
- "The patient's TORCH screen was negative, making congenital infection less likely." — Test result interpretation