CR
Also written as: CR — complete response
Complete response - complete disappearance of all detectable cancer.
Full Definition
Complete response (CR) is a clinical endpoint indicating the complete disappearance of all detectable cancer as assessed by imaging, physical examination, and laboratory tests. This represents the best possible response to treatment, though it does not guarantee cure as microscopic disease may remain. CR is a standardized response criterion used in clinical trials and practice to evaluate treatment efficacy. The durability of complete response is an important prognostic factor for long-term outcomes.
Usage
Usage note: Always capitalize both letters; distinguish from PR (partial response).
In Context
- "The patient achieved CR after six cycles of immunotherapy." — Response assessment report
- "CR was maintained for 18 months before disease recurrence." — Follow-up documentation