consolidation therapy
Intensive treatment given after initial remission to eliminate residual cancer cells.
Full Definition
Consolidation therapy is intensive treatment administered after achieving initial remission to eliminate any remaining cancer cells and reduce the risk of relapse. This approach is commonly used in hematologic malignancies such as acute leukemia, where initial induction therapy achieves remission but residual disease may remain. Consolidation typically involves high-dose chemotherapy and may include stem cell transplantation. The goal is to achieve a deeper, more durable remission and improve long-term survival outcomes.
Usage
Usage note: Distinguish from maintenance therapy, which is less intensive and given over longer periods.
In Context
- "The patient will receive four cycles of consolidation therapy following successful induction." — Treatment planning document
- "High-dose cytarabine served as consolidation therapy for the acute myeloid leukemia." — Medical record