histology
The microscopic study of tissue structure and the specific tissue type of a tumor.
Full Definition
In oncology, histology refers to the microscopic examination of tissue specimens to determine the specific type and characteristics of cancer cells. Histologic classification is fundamental to cancer diagnosis, staging, and treatment planning. Different histologic types within the same organ can have vastly different prognoses and treatment responses. Histology encompasses cell morphology, architectural patterns, and tissue organization. Accurate histologic diagnosis requires expertise in pathology and may involve special stains, immunohistochemistry, or molecular techniques. Treatment protocols are often histology-specific, making precise classification essential.
Usage
Usage note: Always specify the complete histologic diagnosis including subtype when documenting cancer cases.
In Context
- "The histology confirmed invasive ductal carcinoma of the breast." — Pathology report
- "Treatment recommendations vary significantly based on lung cancer histology." — Tumor board discussion