ILD
Pronunciation: I-L-D
Also written as: ILD — interstitial lung disease
Interstitial lung disease, a serious pulmonary adverse event in cancer treatment.
Full Definition
Interstitial lung disease (ILD) is a group of disorders characterized by inflammation and scarring of the lung interstitium, recognized as a significant adverse event in cancer therapy, particularly with targeted therapies and immunotherapy. ILD can range from asymptomatic radiological changes to life-threatening respiratory failure. The condition requires prompt recognition and management, often necessitating treatment discontinuation and corticosteroid therapy. ILD is a special interest adverse event that requires expedited reporting in clinical trials due to its potential severity and impact on patient outcomes.
Usage
Usage note: ILD requires immediate clinical attention and often leads to treatment modification or discontinuation.
In Context
- "The patient developed grade 2 ILD requiring treatment interruption and corticosteroids." — Adverse event case report
- "ILD incidence was higher in patients with pre-existing lung disease." — Safety analysis subgroup report