thrombocytopenia

Full Definition

Thrombocytopenia is a condition characterized by an abnormally low platelet count in the blood, typically below 150,000 platelets per microliter. In oncology, this condition commonly occurs as a side effect of chemotherapy, which can suppress bone marrow function. Severe thrombocytopenia increases the risk of spontaneous bleeding and may require treatment modifications, platelet transfusions, or growth factor support. Monitoring platelet counts is essential for safe administration of cancer treatments.

Usage

Usage note: Often confused with thrombocytosis (high platelet count) or thrombosis (blood clot formation).

In Context

• "Grade 3 thrombocytopenia required dose reduction of the chemotherapy regimen." — Toxicity assessment
• "The patient developed severe thrombocytopenia necessitating platelet transfusion." — Clinical progress note