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meconium ileus
A bowel obstruction in newborns caused by abnormally thick, sticky meconium, often associated with cystic fibrosis.
Full Definition
Meconium ileus is a form of intestinal obstruction that occurs when thick, tenacious meconium becomes impacted in the ileum of a newborn. This condition is strongly associated with cystic fibrosis, occurring in approximately 15-20% of infants with this genetic disorder. The obstruction may be simple or complicated by perforation, atresia, or volvulus, requiring immediate surgical intervention and specialized NICU care.
Usage
Usage note: Distinguish from meconium plug syndrome, which is typically less severe and not associated with cystic fibrosis.
In Context
- "The newborn's failure to pass meconium and abdominal distension led to a diagnosis of meconium ileus." — surgical consultation note
- "Meconium ileus prompted immediate cystic fibrosis genetic testing and family counseling." — discharge summary
Also known as
meconium plug syndrome
meconium obstruction
Contrasted with
normal meconium passage
Don't confuse with
meconium plug syndrome
Hirschsprung disease
intestinal atresia