periventricular leukomalacia
Pronunciation: pair-ih-ven-TRIK-yoo-lar loo-koh-muh-LAY-shuh
A type of brain injury characterized by softening of white matter tissue near the ventricles, commonly seen in premature infants.
Full Definition
Periventricular leukomalacia (PVL) is a form of white matter brain injury that predominantly affects premature infants. It involves the softening and death of white matter tissue adjacent to the lateral ventricles of the brain. PVL is associated with cerebral palsy, cognitive impairments, and visual disturbances in survivors. The condition is often related to periods of decreased blood flow and oxygen delivery to the developing brain. Diagnosis is typically made through cranial ultrasound or MRI, and the condition requires long-term neurological follow-up and early intervention services.
Usage
Usage note: Often abbreviated as PVL in clinical documentation; ensure correct spelling of 'leukomalacia'
In Context
- "Cranial ultrasound revealed evidence of periventricular leukomalacia in the 28-week gestation infant." — Radiology report
- "Early intervention services were recommended due to the diagnosis of periventricular leukomalacia." — Discharge summary