retinopathy of prematurity
Pronunciation: ret-in-OP-ah-thee of pree-ma-CHUR-ih-tee
An eye disease affecting premature infants characterized by abnormal blood vessel development in the retina.
Full Definition
Retinopathy of prematurity (ROP) is a potentially sight-threatening eye disease that affects premature infants, particularly those born before 31 weeks gestation or weighing less than 1,250 grams. The condition occurs when abnormal blood vessels develop in the retina due to incomplete vascularization at birth combined with exposure to high oxygen levels. ROP is staged from 1 to 5 based on severity, with Stage 5 representing total retinal detachment. Treatment may include laser therapy, anti-VEGF injections, or vitrectomy surgery. Regular ophthalmologic screening is essential for early detection and intervention.
Usage
Usage note: Always specify the stage and zone when documenting ROP findings.
In Context
- "Ophthalmologic examination revealed Stage 2 retinopathy of prematurity requiring close monitoring." — Specialist consultation
- "Prevention of severe retinopathy of prematurity involves careful oxygen management in extremely premature infants." — Clinical protocol