screening algorithm
The systematic decision-making process that determines screening results based on analyte values, ratios, and clinical criteria.
Full Definition
A screening algorithm is a standardized computational and decision-making framework that interprets biochemical results to determine whether a newborn screening result is normal or requires follow-up. These algorithms incorporate single analyte measurements, calculated ratios between analytes, clinical factors such as birth weight and gestational age, and sometimes multi-tiered testing approaches. Algorithms are designed to optimize sensitivity and specificity while considering practical factors such as laboratory capacity and healthcare resources. They are continuously refined based on outcome data and technological advances.
Usage
Usage note: Use as two words unless referring to software/computational implementation.
In Context
- "The revised screening algorithm incorporated birth weight adjustment to reduce false positive rates in premature infants." — program update notification
- "Machine learning approaches are being evaluated to enhance traditional screening algorithms." — research abstract