Peritumoral Enhancement
Contrast uptake in brain tissue immediately surrounding a tumor on MRI, indicating blood-brain barrier disruption.
Full Definition
Peritumoral enhancement refers to contrast material uptake in brain tissue immediately adjacent to a tumor mass on contrast-enhanced magnetic resonance imaging. This finding indicates disruption of the blood-brain barrier in the tissue surrounding the primary lesion and may represent tumor infiltration, reactive changes, or treatment-related effects. In neuro-oncology documentation, the pattern and extent of peritumoral enhancement provide important diagnostic and prognostic information. Editors must distinguish this term from enhancement within the tumor itself and understand that peritumoral enhancement can complicate treatment planning and response assessment.
Usage
Usage note: Distinguish from peritumoral edema, which represents fluid accumulation rather than contrast enhancement.
In Context
- "Post-contrast images demonstrated significant peritumoral enhancement extending into the adjacent white matter." — MRI report
- "The extent of peritumoral enhancement may influence surgical planning decisions." — Multidisciplinary team notes