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Neuro Oncology Glossary

100 terms total — 24 showing — Last updated 15 Sep 2026

oligodendroglioma

Professional Technical IVT

A type of brain tumor arising from oligodendrocytes, characterized by fried-egg appearance on histology and often carrying 1p/19q codeletion.

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1p/19q codeletion

Professional Technical IVT

A chromosomal alteration involving loss of chromosome arms 1p and 19q, serving as a key diagnostic and prognostic biomar...

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anaplastic astrocytoma

Professional Technical IVT

A grade III malignant brain tumor arising from astrocytes, characterized by increased cellularity and mitotic activity c...

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awake craniotomy

Intermediate Technical IVT

A surgical technique where patients remain conscious during tumor resection to preserve neurological function.

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bevacizumab

Intermediate Technical IVT

A monoclonal antibody targeting VEGF, commonly used in recurrent glioblastoma with specific imaging considerations.

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blood-brain barrier

Intermediate Technical IVT

A selective barrier that restricts drug delivery to brain tumors, central to neuro-oncology treatment discussions.

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Brachytherapy

Professional Technical IVT

Radiation therapy technique where radioactive sources are placed directly into or near the tumor tissue.

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Brainstem Glioma

Professional Technical IVT

A rare primary brain tumor arising from glial cells within the brainstem structures (midbrain, pons, medulla).

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carmustine wafer

Intermediate Technical IVT

Biodegradable polymer implant containing chemotherapy agent placed directly into the tumor cavity during surgery.

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central nervous system lymphoma

Advanced Technical IVT

Primary or secondary lymphoma affecting the brain, spinal cord, or cerebrospinal fluid compartments.

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Cerebellar Mutism

Intermediate Technical IVT

Temporary loss of speech following posterior fossa surgery, particularly involving the cerebellar vermis.

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cerebellar mutism syndrome

Advanced Technical IVT

Post-operative complication following posterior fossa tumor surgery characterized by loss of speech and other neurologic...

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Cerebral Salt-Wasting Syndrome

Professional Technical IVT

Condition of excessive sodium loss and volume depletion following brain surgery or in patients with intracranial lesions...

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cerebrospinal fluid cytology

Professional Technical IVT

Microscopic examination of cerebrospinal fluid for malignant cells, essential for diagnosing leptomeningeal disease in n...

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Cerebrospinal Fluid Diversion

Professional Technical IVT

Surgical procedures to redirect cerebrospinal fluid when normal drainage is obstructed by tumor or treatment effects.

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choroid plexus papilloma

Professional Technical IVT

A rare benign tumor arising from the choroid plexus epithelium, most commonly occurring in the lateral ventricles of chi...

CPP
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choroidal fissure approach

Professional Technical IVT

A minimally invasive neurosurgical technique for accessing intraventricular tumors through the natural choroidal fissure...

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contrast extravasation

Intermediate Technical IVT

Leakage of contrast material from blood vessels into brain tissue, often indicating blood-brain barrier breakdown in are...

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corpus callosotomy

Advanced Technical IVT

A surgical procedure involving division of the corpus callosum, sometimes performed for tumor resection or seizure contr...

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Corpus Callosum Involvement

Intermediate Technical IVT

Tumor extension into or through the corpus callosum, often indicating aggressive behavior and poor prognosis.

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Cortical Dysplasia

Professional Technical IVT

Developmental malformation of cerebral cortex that may be associated with brain tumors or seizures.

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craniopharyngioma

Professional Technical IVT

A benign tumor arising from embryonic remnants of Rathke's pouch, typically located in the sellar and suprasellar region...

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Craniospinal Radiation

Professional Technical IVT

Radiation therapy technique that treats the entire central nervous system pathway from brain to spinal cord.

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cytoreductive surgery

Intermediate Technical IVT

Surgical procedure aimed at removing as much visible tumor as possible to reduce tumor burden.

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Cytotoxic Edema

Advanced Technical IVT

Intracellular brain swelling caused by cellular energy failure, often seen with acute tumor-related ischemia or treatmen...

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