Neuro Oncology Glossary
100 terms total — 24 showing — Last updated 15 Sep 2026
oligodendroglioma
A type of brain tumor arising from oligodendrocytes, characterized by fried-egg appearance on histology and often carrying 1p/19q codeletion.
1p/19q codeletion
A chromosomal alteration involving loss of chromosome arms 1p and 19q, serving as a key diagnostic and prognostic biomar...
anaplastic astrocytoma
A grade III malignant brain tumor arising from astrocytes, characterized by increased cellularity and mitotic activity c...
awake craniotomy
A surgical technique where patients remain conscious during tumor resection to preserve neurological function.
bevacizumab
A monoclonal antibody targeting VEGF, commonly used in recurrent glioblastoma with specific imaging considerations.
blood-brain barrier
A selective barrier that restricts drug delivery to brain tumors, central to neuro-oncology treatment discussions.
Brachytherapy
Radiation therapy technique where radioactive sources are placed directly into or near the tumor tissue.
Brainstem Glioma
A rare primary brain tumor arising from glial cells within the brainstem structures (midbrain, pons, medulla).
carmustine wafer
Biodegradable polymer implant containing chemotherapy agent placed directly into the tumor cavity during surgery.
central nervous system lymphoma
Primary or secondary lymphoma affecting the brain, spinal cord, or cerebrospinal fluid compartments.
Cerebellar Mutism
Temporary loss of speech following posterior fossa surgery, particularly involving the cerebellar vermis.
cerebellar mutism syndrome
Post-operative complication following posterior fossa tumor surgery characterized by loss of speech and other neurologic...
Cerebral Salt-Wasting Syndrome
Condition of excessive sodium loss and volume depletion following brain surgery or in patients with intracranial lesions...
cerebrospinal fluid cytology
Microscopic examination of cerebrospinal fluid for malignant cells, essential for diagnosing leptomeningeal disease in n...
Cerebrospinal Fluid Diversion
Surgical procedures to redirect cerebrospinal fluid when normal drainage is obstructed by tumor or treatment effects.
choroid plexus papilloma
A rare benign tumor arising from the choroid plexus epithelium, most commonly occurring in the lateral ventricles of chi...
choroidal fissure approach
A minimally invasive neurosurgical technique for accessing intraventricular tumors through the natural choroidal fissure...
contrast extravasation
Leakage of contrast material from blood vessels into brain tissue, often indicating blood-brain barrier breakdown in are...
corpus callosotomy
A surgical procedure involving division of the corpus callosum, sometimes performed for tumor resection or seizure contr...
Corpus Callosum Involvement
Tumor extension into or through the corpus callosum, often indicating aggressive behavior and poor prognosis.
Cortical Dysplasia
Developmental malformation of cerebral cortex that may be associated with brain tumors or seizures.
craniopharyngioma
A benign tumor arising from embryonic remnants of Rathke's pouch, typically located in the sellar and suprasellar region...
Craniospinal Radiation
Radiation therapy technique that treats the entire central nervous system pathway from brain to spinal cord.
cytoreductive surgery
Surgical procedure aimed at removing as much visible tumor as possible to reduce tumor burden.
Cytotoxic Edema
Intracellular brain swelling caused by cellular energy failure, often seen with acute tumor-related ischemia or treatmen...