RANO criteria
Also written as: RANO — Response Assessment in Neuro-Oncology
Standardized response assessment guidelines for neuro-oncology trials, essential for consistent editorial treatment of efficacy data.
Full Definition
Response Assessment in Neuro-Oncology (RANO) criteria provide standardized guidelines for evaluating treatment response in brain tumor clinical trials. These criteria address the unique challenges of assessing brain tumors, including the effects of corticosteroids, pseudoprogression, and non-enhancing tumor components. RANO criteria incorporate clinical assessment alongside imaging findings and have specific adaptations for different tumor types. Editors must understand these criteria when reviewing efficacy data and ensure consistent terminology when describing response categories.
Usage
Usage note: Always specify which version of RANO criteria used; distinguish from iRANO (immunotherapy-specific) criteria when applicable.
In Context
- "Tumor response was assessed using RANO criteria with independent radiological review." — Clinical trial methodology
- "The patient achieved a partial response according to RANO criteria maintained for 8 months." — Clinical efficacy report