optic atrophy
Degeneration or loss of optic nerve fibers resulting in pallor of the optic disc.
Full Definition
Optic atrophy represents the end-stage result of various pathological processes affecting the optic nerve, characterized by loss of nerve fibers and resultant pallor of the optic disc. The condition may be partial or complete, and can result from numerous causes including ischemia, compression, inflammation, or hereditary conditions. Clinically, it presents with reduced visual acuity, visual field defects, and characteristic pale appearance of the optic nerve head on fundoscopy.
Usage
Usage note: Distinguish from optic neuritis, which is an inflammatory condition that may lead to optic atrophy.
In Context
- "The patient developed secondary optic atrophy following resolution of chronic papilledema." — Clinical case report
- "Fundoscopic examination revealed temporal pallor consistent with early optic atrophy." — Ophthalmology consultation note