Parinaud syndrome
Pronunciation: PAIR-in-oh syndrome
Dorsal midbrain syndrome causing vertical gaze paralysis and pupillary abnormalities.
Full Definition
A neurological syndrome resulting from lesions in the dorsal midbrain affecting the pretectal area and posterior commissure. Characterized by paralysis of upward gaze, convergence-retraction nystagmus, and light-near dissociation of the pupils. Often associated with hydrocephalus, pineal tumors, or vascular lesions. Editors should note the distinction from isolated vertical gaze palsies and the specific pupillary findings.
Usage
Usage note: Named after Henri Parinaud; capitalize the P in Parinaud but not syndrome.
In Context
- "The patient presented with classic Parinaud syndrome following resection of a pineal region tumor." — Neurosurgical consultation report
- "Parinaud syndrome should be distinguished from other causes of vertical gaze limitation in the differential diagnosis." — Clinical assessment note