PERG
Pronunciation: perg
Also written as: PERG — pattern electroretinogram
Pattern electroretinogram, a specialized test measuring retinal ganglion cell function important in optic nerve disease evaluation.
Full Definition
The pattern electroretinogram (PERG) is an electrophysiological test that specifically measures the function of retinal ganglion cells by recording electrical responses to a reversing checkerboard pattern. Unlike the full-field ERG, which primarily reflects photoreceptor function, the PERG is sensitive to ganglion cell dysfunction and is particularly valuable in evaluating optic nerve diseases such as glaucoma, optic neuritis, and compressive optic neuropathy. The test provides objective evidence of retinal ganglion cell dysfunction before structural changes become apparent on imaging or visual field defects develop.
Usage
Usage note: Spell out as 'pattern electroretinogram' on first use; distinguish from full-field ERG in documentation.
In Context
- "PERG demonstrated reduced amplitude consistent with retinal ganglion cell dysfunction." — Electrophysiology report
- "The normal PERG helped exclude retinal pathology in the patient with unexplained visual loss." — Differential diagnosis evaluation