neuronal tumor
Brain neoplasm composed predominantly of mature neuronal cells, often with mixed glial components.
Full Definition
Neuronal tumor is a category of brain neoplasms composed primarily of differentiated neuronal cells, which may occur alone or in combination with glial elements (forming neuronal and mixed neuronal-glial tumors). These tumors typically express neuronal markers such as synaptophysin and neurofilament protein, and often present with seizures due to their cortical location. Examples include gangliocytoma, ganglioglioma, and central neurocytoma. They generally have favorable prognoses compared to pure glial tumors.
Usage
Usage note: Distinguish from neuronal-glial mixed tumors; specify immunomarker profile when available.
In Context
- "The tumor showed strong synaptophysin positivity, confirming its classification as a neuronal tumor." — Immunohistochemistry report
- "This well-differentiated neuronal tumor was associated with long-standing temporal lobe epilepsy." — Clinical pathology correlation