cerebral perfusion pressure
The pressure gradient driving blood flow to the brain, calculated as mean arterial pressure minus intracranial pressure.
Full Definition
Cerebral perfusion pressure represents the net pressure gradient that drives cerebral blood flow, calculated using the formula CPP = MAP - ICP. Maintaining adequate CPP (typically >60-70 mmHg) is crucial in neurocritical care to ensure sufficient oxygen and glucose delivery to brain tissue. Low CPP can lead to cerebral ischemia, while excessively high CPP may worsen cerebral edema.
Usage
Usage note: Spell out fully when first mentioned; CPP acceptable thereafter
In Context
- "The goal is to maintain cerebral perfusion pressure above 60 mmHg." — Treatment protocol
- "Cerebral perfusion pressure optimization required both ICP reduction and blood pressure support." — Case report