CPP
Also written as: CPP — Cerebral Perfusion Pressure
Cerebral perfusion pressure; the pressure gradient driving blood flow to the brain, calculated as MAP minus ICP.
Full Definition
Cerebral perfusion pressure (CPP) represents the pressure gradient that drives cerebral blood flow and is calculated as mean arterial pressure (MAP) minus intracranial pressure (ICP). Normal CPP ranges from 60-70 mmHg in adults. Maintaining adequate CPP is crucial in neurocritical care to prevent secondary brain injury from cerebral ischemia. CPP targets may vary based on individual patient factors and underlying pathology. In clinical documentation, CPP values and the interventions used to optimize them (such as blood pressure management or ICP reduction) must be carefully recorded.
Usage
Usage note: Always reference target ranges and calculation components (MAP-ICP).
In Context
- "CPP was maintained above 60 mmHg through vasopressor support and ICP management." — Intensive care note
- "Decreased CPP to 45 mmHg prompted immediate intervention with mannitol." — Emergency response documentation