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cytogenic edema
Pronunciation: sigh-toe-JEN-ik
Brain swelling caused by cellular injury and breakdown of the blood-brain barrier, distinct from cytotoxic edema.
Full Definition
Cytogenic edema represents brain swelling that results from cellular damage and blood-brain barrier disruption, leading to both intracellular and extracellular fluid accumulation. Unlike pure cytotoxic edema (which is intracellular) or vasogenic edema (which is extracellular), cytogenic edema involves both compartments simultaneously. This type of edema commonly occurs in severe traumatic brain injury and is associated with cellular membrane failure and inflammatory responses.
Usage
Usage note: Distinguish from cytotoxic and vasogenic edema; represents mixed pathophysiology
In Context
- "MRI findings suggested cytogenic edema with both restricted diffusion and T2 hyperintensity." — Radiology report
- "The patient developed cytogenic edema following severe traumatic brain injury." — Neurology consultation
Don't confuse with
cytotoxic edema
vasogenic edema
cellular edema