SISCOM
Pronunciation: SIS-kom
Also written as: SISCOM — Subtraction Ictal SPECT Co-registered to MRI
Subtraction ictal SPECT co-registered to MRI, a neuroimaging technique for epilepsy localization.
Full Definition
SISCOM (Subtraction Ictal SPECT Co-registered to MRI) is a nuclear medicine neuroimaging technique used in epilepsy evaluation that combines ictal and interictal SPECT scans with structural MRI data. The process involves subtracting the interictal SPECT from the ictal SPECT to highlight areas of increased blood flow during seizures, then co-registering this difference image to high-resolution MRI for anatomical correlation. This technique helps identify the seizure onset zone by revealing hyperperfusion patterns that occur during ictal events, making it particularly valuable in cases where other localization methods are inconclusive.
Usage
Usage note: Always capitalize as acronym; spell out fully on first use in formal reports.
In Context
- "SISCOM imaging demonstrated focal hyperperfusion in the right temporal lobe during seizure activity." — Presurgical epilepsy evaluation
- "The SISCOM study was concordant with EEG findings, supporting surgical candidacy." — Multidisciplinary team report